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Messages - Puckoon

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1
General discussion / Re: The Many Faces of US Politics...
« on: January 17, 2018, 06:25:44 PM »
Don given a clean bill of health by the White House Doctor

6'3 tall and weighing 239 lbs - which puts him 1 inch or 1lb short of being clinically obese.

Here is 6'3 Trump standing next to 6'1 Obama

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and next to 6'2 Trudeau

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There's already been the birther movement - is this the start of the girther movement?

Haha...good one

Im sure there was some fudging of the numbers, but you should use different photos if you want to prove your point.  First photo, trump is leaning sideways so thats no good......second one Trumps shoulder is noticeably higher than Trudeaus, so he actually does look taller.  Hard to tell with the mop of hair

Where's Ballinaman? He can settle this once and for all. Master of angles on Gaaboard evidence!

2
General discussion / Re: Death Notices
« on: January 15, 2018, 05:50:33 PM »
Remember bouncing around in youth club discos to a local band busting out Zombie and other 90's era classics. RIP, far too young.

3
General discussion / Re: Aussie Flu
« on: January 11, 2018, 05:46:03 PM »
Joe,

If you read the PNAS article and then read the NBC (not fake news) article, you can see how they've butchered the material and you don't need to go beyond the second sentence to find this...

Quote
Flu viruses mutate every year and it turns out the methods used to make flu vaccines cause them to mutate even more, the researchers found.

First half, correct. Second half, misleading. Yes the Flu virus mutates every year. Yes, the methods used to make flu vaccines leave the flu vaccine itself open to mutation. That vaccine is open to mutation based on how it is grown in the egg system. The flu vaccine does not cause the flu virus that we are susceptible to, to mutate. The avian egg growth system may cause the flu virus in the vaccine, to mutate. Huge difference, but it can lead to issues in efficacy. There is considerable research efforts to finding another vaccine systems that reduce the % probability of antigenic mismatches between vaccine virus and circulating virius - but the egg system is stable, and fully equipped to do the job. The virus just has the ability to outsmart it sometimes. The same virus has the ability to outsmart us, and continually find ways to mutate and adapt.

Big Pharma is involved in the manufacture process of flu vaccine and this is another reason that the enlightened public can trend so heavily against it. Big Pharma is bad... etc, but that's another topic. GSK, Sanofi Pasteur and Novartis are the 3 main players (smaller companies don't get involved in the manufacture and sale of the flu vaccine of the year - primarily due to the scale of manufacture needed in the short time span window).

Public Health Agencies and funded research labs (think universities, CDC etc) examine the strains from each hemisphere which has a different flu season and are able to work on predictive models based on strains that are found in the opposing hemisphere in their respective flu season. From this the PHAs provide seed strains to the main pharmaceutical companies who either have in house regulated manufacturing capabilities (a rare and no mean feat feature of a pharmaceutical company), or a strong relationship with a Contract Manufacturing System who is on alert to produce the quantities needed to match the demand. Each vaccine is usually comprised of 3-4 strains, 4 being the most recent successful flu development. There are models actively being researched to find a universal vaccine which is efficacious independent of strain. Timelines projected for this around 8-10 years.

Drug development is an insanely complex logistical challenge. Supply chain, release and stability data and the drug passport considerations that are required to accompany any product designed for human use - on top of the proof of concept and R&D work that precedes any human designed manufacture is mind blowing in its enormity.

4
General discussion / Re: Aussie Flu
« on: January 09, 2018, 05:40:57 PM »
At the risk of being thrown in the dungeon as an antivaxer..... Ive a few questions

Is there any good reason for not getting a flu shot?
Is there any point to putting a load of chemicals, preservatives and other crap into my body that I probably wont need?
Do medical professionals play it save and use the law of averages for the population when dealing with individuals and thereby declare that pretty much everyone should get it.
Am I making my immune system weaker in the long term?

None

Rather angled description of the vaccine. Think of a flu shot as insurance for your car/home. Hopefully you never need those either but you avail of their protection. The flu shot usually has the virus itself. That virus is deactivated by miniscule amounts of formaldehyde. Yes. Sounds scary and awful but it’s in the parts per tens of millions. Usually there’s an adjuvant like aluminum, again the PPM range. Then there’s some gelatin. A common stabilizer which keeps the vaccine suitable for use between manufacture and administration. It’s usually porcine gelatin so many vaccines will come with a warning for those with pork allergies.

Wish I had pork allergies over xmas!

So can anyone avail of the flu jab? I thought the very young and the old only

Can’t speak for at home but yes in the US anyone can, and should get vaccinated. I get it every year (in honesty I haven’t this year yet as I’ve just not been organized enough). Many employers bring a team onsite for their employees or you can get it in any pharmacy or doctors office.

If you think about it, the less people with the flu - the better off the very young and the very old are.


5
General discussion / Re: Aussie Flu
« on: January 09, 2018, 04:04:29 PM »
At the risk of being thrown in the dungeon as an antivaxer..... Ive a few questions

Is there any good reason for not getting a flu shot?
Is there any point to putting a load of chemicals, preservatives and other crap into my body that I probably wont need?
Do medical professionals play it save and use the law of averages for the population when dealing with individuals and thereby declare that pretty much everyone should get it.
Am I making my immune system weaker in the long term?

None

Rather angled description of the vaccine. Think of a flu shot as insurance for your car/home. Hopefully you never need those either but you avail of their protection. The flu shot usually has the virus itself. That virus is deactivated by miniscule amounts of formaldehyde. Yes. Sounds scary and awful but it’s in the parts per tens of millions. Usually there’s an adjuvant like aluminum, again the PPM range. Then there’s some gelatin. A common stabilizer which keeps the vaccine suitable for use between manufacture and administration. It’s usually porcine gelatin so many vaccines will come with a warning for those with pork allergies.

6
General discussion / Re: Aussie Flu
« on: January 08, 2018, 11:22:38 PM »
The so called "Aussie flu" is the flu that was here last year (A1 strain???). If you've got the flu jab you're covered. There's another strain here this year (B1 I think) that the flu jab only gives limited cover to and is a nasty dose too. Apparently it's 50/50 between the two which is supposedly unusual. It's not too late to get the flu jab. Next 4-6 weeks will see a lot of the virus....I'm getting the jab tomorrow. I usually have got it but so one reason or another haven't got it yet this winter.

Too young and fit to get the jab!

Wrong.

7
General discussion / Re: Sinn Fein? They have gone away, you know.
« on: January 06, 2018, 03:50:38 PM »
Unfortunately that’s the best explanation. The worst explanation is the one that will be clung to

9
General discussion / Re: Corny One for Friday
« on: January 05, 2018, 07:45:14 PM »
So The Beach Boys Walk into a bar...

Round?
A round?
Get a round?

I'll get a round.

Yea? Get a round?
A round?
Round?
Ill get a round..

10
General discussion / Re: Official Gooners Thread aka Déjà vu
« on: January 03, 2018, 09:49:28 PM »
Well, Room for optimism? Wilshire, Maitlin Niles, and we can always play Mustafi and Hector up top when Sanchez and Ozil go.

Pessimism? Entire Defence - Penalty was soft, but still a PK. Bellerin has been rash a few times in the box this year.

11
General discussion / Re: Official Gooners Thread aka Déjà vu
« on: January 02, 2018, 06:15:13 PM »
Anyway, what's to be scared of? Abject failure?

12
General discussion / Re: Official Gooners Thread aka Déjà vu
« on: January 02, 2018, 06:06:01 PM »
If he's not staying for the long haul, ship him out. Workrate has been better over the holidays but Jim Beglin commented during the WBA game that of the arsenal outfield players this season - Sanchez has run the least. Some flip flop on his earlier effort.

13
General discussion / Re: Boxing Day
« on: December 27, 2017, 06:30:23 PM »
Had a nice brunch with the spouse then played golf. Hit my first Hole In One on the 17th at the end of what was a pretty shitty round!

Proceeded to get well toasted in the clubhouse (thank f**k for insurance, bar tab was ridiculous) and went out to dinner with some friends and am currently suffering the tequila sunrise.

Whatever it’s called, it’s always been my favorite day of the year and yesterday was no exception

14
General discussion / Re: The Many Faces of US Politics...
« on: December 21, 2017, 04:55:54 PM »
Believe what you want....if you think that was an official policy position of the Republican party thats your perogative, but in my view its just fake news and spin


Fact checkers judged this statement to be half true....if you want to hang your hat on half truths, well thats on you,



If I went back and looked at every think thank that ever advised the Democratic Party Im sure I could find some very interesting suggestions that never saw the light of day in any meaningful way

Maybe a good way to start squaring this endless circle is with some agreeable definitions.

What is a half truth?

What is fake news?

If it is a half truth that my wife had an affair - would I consider it to be fake news?

15
General discussion / Re: Christmas cards
« on: December 19, 2017, 02:34:35 PM »
Nah, they're double sided now. You have to make sure there's a photo of the Dog included and space is at a premium for sending well wishes.

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